Weight Loss Information logo

Axokine Weight Loss Drug Information
Bypasses Leptin Satiety Control in Brain to Reduce Appetite
Weight Loss Information

Benefits & Health Side Effects of New Types of Obesity Drugs to Control Eating & Calorie Intake

Axokine Weight Loss Drug

Questions About Obesity Medications
Appetite Suppressants - Anti-Obesity Drugs - Prescription Obesity Drugs
Development of Diet Pills - Meridia Short-Term Obesity Drug - Xenical Lipase Inhibitors - Xenical Study
Orlistat & Obesity Management - Orlistat Weight Loss Study - Sibutramine FDA Approved Obesity Drug
Sibutramine Study - Obesity Drugs & Diabetes - Risks of Weight Loss Pills - Adipex Obesity Drug
Side Effects of Adipex - Phentermine to Reduce Appetite - Side Effects of Phentermine

Axokine is a brand new drug with hopes of being a totally different kind of weight-loss drug. It's a man-made chemical that mimics a chemical the brain makes to protect itself from injury. It was designed as a possible treatment for Lou Gehrig's disease. But when researchers gave the experimental drug to patients, they lost weight.

Axokine Weight Loss Drug Affects Leptin

Later experiments showed why. The drug affects a powerful brain system called the leptin pathway. Leptin is a chemical messenger that tells you when you've had enough to eat. Obese people have leptin resistance; they lose the ability to know when they're full. Axokine apparently bypasses this resistance and flips the fullness switch.

Axokine Weight Loss Drug - Study

Mark P. Ettinger of Regeneron Pharmaceuticals Inc. in Tarrytown, N.Y., and colleagues performed the first study of Axokine's role as a weight-loss drug in obese people.

They put 173 of these volunteers on a low-calorie diet. Some got fake placebo injections. Others got various injection doses of Axokine. The study was funded by Axokine's manufacturer, Regeneron Pharmaceuticals Inc.

After 12 weeks, those on the diet alone gained about a fifth of a pound. Those getting what turned out to be the best dose of Axokine lost an average of nine pounds.

Axokine Weight Loss Drug - No Immediate Weight Gain

Perhaps the best news came in the year-long period after treatment. There was no immediate weight gain when drug treatment stopped. After about a year, patients treated with Axokine started to gain some weight.

Axokine Weight Loss Drug - Side Effects

There was a high rate of side effects reported for both the weight-loss drug Axokine and placebo. Side effects that appeared linked to Axokine treatment included skin reactions at the site of injection, nausea, and increased cough. These last two side effects weren't as much a problem in those who got the best dose of Axokine.

A large, ongoing phase III clinical trial is now delving further into Axokine's role as a safe, weight-loss drug in obese people.

SOURCE: The Journal of the American Medical Association, April 9, 2003.


Weight loss information - Rapid Weight Loss - Diet Program - How to Lose Weight - Best Weight Loss Goals
Weight Loss Advice - Healthy Balanced Diet - Body Fat Percentage - Diets & Weight Loss Programs
Information on Weight Loss Diets - How to Reduce Weight - Weight Management - Weight Loss Surgery Information
Surgery Benefits/Risks - Weight Loss Drugs Advice - Weight Loss Pills / Weight Loss Pills Information
Xenical Weight Loss Drugs - Meridia/Sibutramine Pills - Guide to Diet Pills - Calorie Needs - Weight Loss Supplements
How to Control Weight - Body Mass Index Calculator - Exercise & Fitness to Lose Weight - Weight Health Issues - Obesity
Treatment of Obesity - Advice About Weight Loss - Questions on Weight Loss & Diet - Weight Loss Advice for Women
Weight Loss Advice for Diabetics - Weight Loss Advice for Teenagers - Weight Loss Advice for Adolescents
Diet & Weight Information - Weight Loss Support - Obesity Drug Treatment - Obesity & Gallstones - How to Lower Cholesterol
Dietary Guidelines - Protein, Carbs & Diet - Carbohydrates & Weight Loss - Weight Gain at College
Weight Gain After Quit Smoking - Weight Control in Menopause - Weight Gain in Pregnancy - Weight Control in Pregnancy
Weight Loss Breast-Feeding - Healthy Weight Range - Healthy Weight Loss Diet - Waist Circumference - Weight Cycling
Weight Health Risks - Weight Risks Assessment - Weight Reduction Tips - Weight Loss Guidelines - Weight Loss Products
Weight Loss Tools - Weight Maintenance

Enquiries: Contact Us. See also Terms of Use
© 2003-2018 Weight Loss Information. All Rights Reserved.