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Obesity and Fat Cells
Adipocytes, Pre-adipocytes and the Development of Excess Body Fat
Advice About Reducing Body Fat - How to Reduce Weight

Obesity & Fat Cells

Fat research is relatively new. It was only in the 1950s that a French physician showed that upper-body fat - not lower - seemed to be closely associated with certain types of diseases.

In Dr. Sorisky's molecular research, he is looking at why pre-fat cells, of which the body has many millions, turn into fat cells. What triggers them?

Specifically, he is working with an established line of fat cells called adipocytes and their precursors, called pre-adipocytes. When the pre-fat cells are exposed to certain hormones or fatty acids, they can be induced to grow into fat cells.

He cautions, however, that his lab is not looking for a magic pill or drug that will eradicate weight gain. If only it were so easy.

"Ultimately what I think is important is to get away from one size fits all (in terms of a solution)," says Dr. Sorisky. "It's going to be important to individualize what is going on in people."

By "individualization," he is referring to a person's genetic makeup, diet and lifestyle. In theory, if a doctor knew the link between the gene, the fat type and the individual, the physician could better prescribe treatment, whether it be a specific kind of diet or exercise.

"We have to know more about an individual person, with their genes, with their environment, and know how we're going to tailor approaches."

For next page, click Obesity, Fat & Genes

See:
Obesity Fat Research
Obesity Fat Cells
Obesity, Fat & Genes
Obesity, Fat & Insulin

Obesity and Weight Loss
Obesity is now the "trillion dollar disease". This reflects the social costs of obesity, in health and lost production, as well as the weight loss drug profits that might be made for any pharmaceutical company that finds a drug-cure for obesity. The search for viable weight loss medications continues, although pharmaceutical weight loss products still have significant side effects.

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