Weight Loss Exercise Trial
Weight Loss Exercise Study Aim
To determine the time course for changes in aerobic capacity, body weight
(BW), and composition in overweight adults in response to a supervised
exercise trial with a targeted energy expenditure of 2000 kcal week-1.
Weight Loss Exercise Study Method
The Midwest Exercise Trial (MET) was a randomized, controlled, 16-month
verified, supervised exercise trial. Aerobic exercise progressed to 45
min day-1, 5 days week-1 over 6-months and was then maintained for 10
months. Controls maintained their normal physical activity and all participants
maintained ad libitum diets.
Weight Loss Exercise Study Subjects
A total of 131 participants were randomized to exercise or control groups
and 74 completed the intervention and all laboratory testing.
Weight Loss Exercise Study Results
Aerobic capacity increased from baseline to 9 months in exercising men
as well as women with no significant changes occurring at 12 or 16 months.
From baseline to 9 months body weight and fat weight significantly decreased
in exercising men with no changes occurring at 12 or 16 months. There
were no changes in fat-free weight across the 16 months for exercising
men or for body weight or composition in exercising women. Further, there
were no significant changes for the control men for aerobic capacity,
BW, or body composition across 16 months. Women in the control group showed
significant increases in weight of 2.9±5.5 kg and fat weight of
2.1±4.8 kg at 16 months only.
Weight Loss Exercise Study Conclusion
We recommend that investigations that use exercise without diet as the
stimulus for weight loss have at least a 9-month duration to provide sufficient
time for the full effects to be realized, should such effects be present.
International Journal of Obesity (2003)
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