Weight Loss in Obese Men - Clinical Trial
Health-related quality of life in WHO Class
II-III obese men losing weight with very-low-energy diet and behavior
modification: a randomized clinical trial
Weight Loss Study Aim
To study health-related quality of life responses to marked weight loss
in WHO Class II-III (body mass index (BMI) 35 kg/m2) obese men.
Weight Loss Study Method
An 8 month randomize clinical trial with a 4 month weight loss program
(10 weeks on a very-low-energy diet (VLED) and 17 behaviour modification
visits) in the treatment group and no intervention in the control group.
Weight Loss Study Subjects
Nineteen men (mean age 45.9 years, mean BMI 39.3 kg/m2) in the treatment
group and 19 men (47.2 years, 39.4 kg/m2) in the control group.
Weight Loss Study Measurements
Weight and questionnaires measuring health-related quality of life.
Weight Loss Study Results
In the treatment group, the mean weight loss was 17.0 percent at the end
of the 4-month therapy. At the end of follow-up, nearly 6 months after
the end of VLED in the treatment group, the average maintained weight
loss was 13.9 percent of baseline weight. The control group was weight
stable throughout the study. During treatment, there was only transient
improvement in general health, bodily pain, mental health, emotional role
functioning and vitality (all increases in the scores were not statistically
significant). Improvements in physical functioning, social functioning
and obesity-related psychosocial problems were maintained until the end
of follow-up. The treatment group also reported improvement in perceived
health in the past year. There was only minor fluctuation in questionnaire
scores in the control group.
Weight Loss Study Conclusion
The short-term and maintained health-related quality of life effects of
weight loss may differ. Marked weight loss in WHO Class II-III obese men
leads to improvements in physical functioning, social functioning, obesity-related
psychosocial problems, and perceived health; these improvements were maintained
at 4 month post-intervention follow-up.
Source: International Journal of Obesity
(2002)
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