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Q. For how long do I need to take weight-loss pills?

The answer depends upon whether the medication helps you to lose and maintain weight and whether you have any side effects. Because obesity is a chronic disease, any treatment, whether drug or nondrug, may need to be continued for years, and perhaps a lifetime, to improve health and maintain a healthy weight. There is little information on how safe and effective weight-loss medications are for many years of use.

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