Soy Diet & Weight Loss
A novel soy-based meal replacement formula
for weight loss among obese individuals: a randomized controlled clinical
trial.
Soy Weight Loss Study - Aim
To assess the efficacy and safety of a low calorie soy-based meal replacement
program for the treatment of obesity.
Soy Weight Loss Study - Design
A 12-week prospective randomized controlled clinical trial. Setting: Outpatient
weight control research unit. Subjects: One hundred obese (28<BMI<or=41
kg/m(2)) volunteers between the ages of 35 and 65 y. Seventy-four participants
completed the trial.
Soy Weight Loss Study - Intervention
Participants were randomized to either the meal replacement treatment
group (n=50; 240 g/day, 1200 kcal/day) or control group (n=50). Both groups
at baseline received a single dietary counseling session and a pamphlet
describing weight loss practices.
Soy Weight Loss Study - Results
By intent-to-treat analysis, the treatment group lost significantly more
weight than the control group and had a greater change in total and LDL
cholesterol. Among completers only, the treatment group again lost more
weight and had a greater reduction in total cholesterol and a greater
change in LDL cholesterol. (For any given degree of weight loss, the reduction
in LDL cholesterol was significantly greater in the treatment group.)
Treatment was well tolerated and no serious side effects were detected.
Soy Weight Loss Study - Conclusions
Use of this soy-based meal replacement formula was effective in lowering
body weight, fat mass and in reducing LDL cholesterol beyond what could
be expected given the weight lost.
Source: Department of Biostatistics and
Center for Research on Clinical Nutrition, University of Alabama at Birmingham,
Birmingham, Alabama 35294-0022, USA. 2003
Weight Loss Methods
The science of weight loss and obesity management is constantly evolving,
along with research into weight loss drugs, supplements and gastric bypass
surgery. At present, however, a balanced diet combined with regular exercise
remains the favored weight management strategy of most weight loss experts. Return to Weight Loss Data
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