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Soy Diet and Weight Loss
Trial of Soy-Based Meal Replacement Weight Loss Diet Among Obese Patients
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Soy Diet & Weight Loss

A novel soy-based meal replacement formula for weight loss among obese individuals: a randomized controlled clinical trial.

Soy Weight Loss Study - Aim
To assess the efficacy and safety of a low calorie soy-based meal replacement program for the treatment of obesity.

Soy Weight Loss Study - Design
A 12-week prospective randomized controlled clinical trial. Setting: Outpatient weight control research unit. Subjects: One hundred obese (28<BMI<or=41 kg/m(2)) volunteers between the ages of 35 and 65 y. Seventy-four participants completed the trial.

Soy Weight Loss Study - Intervention
Participants were randomized to either the meal replacement treatment group (n=50; 240 g/day, 1200 kcal/day) or control group (n=50). Both groups at baseline received a single dietary counseling session and a pamphlet describing weight loss practices.

Soy Weight Loss Study - Results
By intent-to-treat analysis, the treatment group lost significantly more weight than the control group and had a greater change in total and LDL cholesterol. Among completers only, the treatment group again lost more weight and had a greater reduction in total cholesterol and a greater change in LDL cholesterol. (For any given degree of weight loss, the reduction in LDL cholesterol was significantly greater in the treatment group.) Treatment was well tolerated and no serious side effects were detected.

Soy Weight Loss Study - Conclusions
Use of this soy-based meal replacement formula was effective in lowering body weight, fat mass and in reducing LDL cholesterol beyond what could be expected given the weight lost.

Source: Department of Biostatistics and Center for Research on Clinical Nutrition, University of Alabama at Birmingham, Birmingham, Alabama 35294-0022, USA. 2003

Weight Loss Methods
The science of weight loss and obesity management is constantly evolving, along with research into weight loss drugs, supplements and gastric bypass surgery. At present, however, a balanced diet combined with regular exercise remains the favored weight management strategy of most weight loss experts.

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