Weight Loss Obesity
Information About Prescription Pills to Lose Weight
Weight Loss Drugs
About Obesity Medications
What Are Weight Loss or Diet Drugs?
Weight loss or diet drugs are substances intended to promote weight loss. They may be prescription weight loss pills that must receive approval from the US Food and Drug Administration (FDA) before being sold or administered, or over-the-counter weight loss drugs sold as supplements or diet pills without prescription. Both types of weight loss drugs are available online on the Internet.
Weight Loss Drugs - How Do They Work
Most prescription weight loss and diet drugs work through appetite suppression, but some work by creating an increased feeling of satiety after eating.
A new type of weight loss medication are drugs known as lipase inhibitors, which do not work to suppress appetite but instead block fat absorption in the body.
Most over the counter weight loss drugs act as stimulants to decrease appetite.
Weight Loss Drugs - Mostly Approved for Short Term Use Only
Prescription weight loss drugs require approval from the FDA. Over the counter weight loss drugs do not. Currently, only sibutramine (Meridia) and orlistat (Xenical) are FDA approved for long-term use. Most weight loss and diet drugs are intended to be used only temporarily and are most effective when combined with other lifestyle changes. Over the counter weight loss drugs have similar short-term efficacy.
Weight Loss Drugs - Who Are They For
General Weight Loss
Weight Loss Drugs - A Short History
Thyroid Weight Loss Drugs and Others
Amphetamine Weight Loss Drugs
Phenylpropanolamine-based Weight Loss
Fen/Phen Weight Loss Drugs
Herbal Fen/Phen Weight Loss Drugs
Meridia and Ephedra-based Weight Loss
Weight Loss Drugs - Little Testing
Historically, weight-loss drugs have been subjected to very little testing; almost no long-term studies have been produced. Research indicates that risks of drugs such as fenfluramine, phentermine, and dexfenfluramine increase dramatically the longer the drugs are used. In addition, the drugs produce minimal weight loss, and upon discontinuing the use of any of the drugs, the weight is virtually always regained. For example, amphetamines produce an average loss of 10-20 pounds before the drug loses effectiveness, and dexfenfluramine produces an average of six pounds of weight loss when compared to a placebo. Further, anecdotal evidence suggests that consumers eager to speed weight loss frequently take multiple, more dangerous doses of weight-loss drugs. Vulnerable consumers have also been misled and harmed by unregulated herbal, so-called "natural," weight-loss drugs.
Weight Loss Drugs - Continued Growth
Despite the lack of effectiveness and the risks associated with every past weight-loss drug, a variety of new weight-loss drugs are currently up for approval, or are in the research and development stage. A drug to regulate leptin, a satiety hormone secreted by fat tissue, is being developed. In addition, a drug to decrease appetite by blocking neuropeptide-Y and a drug to regulate metabolism by stimulating beta-3 adrenergic receptors are being researched.
Weight Loss Drugs - Consent, Truth About Obesity Health Risks
Weight-loss drug promoters emphasize the drugs' supposed health benefits and minimize risks related to taking the drugs, so that consumers cannot truly give informed consent prior to taking the drugs. There is also some controversy concerning the extent and severity of the health risks associated with being fat. According to the US Surgeon-General and mainstream weight-loss expert opinion, obesity and obesity-related diseases are best reduced through weight loss. But according to the National Association to Advance Fat Acceptance (NAAFA), scientific research on file at the NAAFA headquarters demonstrates that many fat people are already healthy, and that a person's health status can be improved independent of weight loss by making positive lifestyle changes in exercise, stress management, healthy eating, and positive social support. See also: Obesity & Drug Treatment for Weight Loss
Weight Loss Drugs - FDA Regulation
Currently, the agency responsible for regulating weight-loss drugs, the US Food and Drug Administration, appears to bow to pressure from drug companies to approve weight-loss drugs without requiring sufficient long-term testing, and has not demonstrated a commitment to guard the public's health. In reply, the FDA points to lack of finance as well as lack of congressional support for weight loss drugs reform. See also Dietary Supplements & FDA Regulation and Weight Loss Drugs Information
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