Body Fat & Metabolic Syndrome Risk
Fat & Metabolic Syndrome Study Background
Increasing attention has focused on the association between body fatness
and related metabolic risk factors. The quantitative link between percentage
body fat and the risk of metabolic syndrome is unknown.
Fat & Metabolic Syndrome Study Aim
Determine the risk [odds ratios (ORs)] of metabolic syndrome based on
percentage body fat in black and white men and women in the United States
and to provide corresponding ranges of percentage body fat associated
with a risk equivalent to body mass index (BMI; in kg/m2).
Fat & Metabolic Syndrome Study Methods
Subjects were participants in the third National Health and Nutrition
Examination Survey and were divided into those with and without the metabolic
syndrome. OR equations were derived from logistic regression models for
percentage body fat and BMI, with the 25th percentile in the study population
as the reference. Ranges were developed by associating percentage body
fat with the equivalent risk of metabolic syndrome based on established
BMI cutoffs.
Fat & Metabolic Syndrome Study Results
Results: Four sets (men, women, black, and white) of OR curves were generated
for percentage body fat and for BMI by using data from 8259 adults. The
ORs for metabolic syndrome were lower in blacks than in whites at any
given percentage body fat or BMI. The developed cutoffs for percentage
body fat differed between men and women but showed only small race and
age effects. A simplified set of sex-specific percentage body fat ranges
for the risk of metabolic syndrome were developed.
Fat & Metabolic Syndrome Study Conclusion
The risk of metabolic syndrome can be established from measured percentage
body fat by using either the developed OR curves or percentage body fat
thresholds at traditional BMI cutoffs. This information should prove useful
in both clinical and research settings.
Source: American Journal of Clinical Nutrition
2003
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