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Weight Loss Drugs - Depression
Sibutramine and Orlistat Obesity Drugs Not Yet Linked With Depression Disorders
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Weight Loss Drugs - Depression Disorders

Weight Loss Drugs & Depression
A variety of drugs used to assist with weight loss have been implicated in the precipitation or induction of depression type disorders. This is true of a large number of phenylethylamine agents possessing psychostimulant properties, non-phenylethylamine psychostimulants (e.g., caffeine) and the serotonergic agent, fenfluramine.

Weight Loss Drugs - Sibutramine & Orlistat
There is, as yet, no substantial evidence linking the more modern weight loss drugs, sibutramine and orlistat, to the aetiology of major depression. Nevertheless, when these drugs are used, major depression will continue to be an important clinical consideration because of the elevated frequency with which major depression occurs in obese patients, the contribution that major depression may make to poor outcomes in non-pharmacological weight loss treatment and because of the interplay between symptoms of depression and weight loss treatment.

Source: Scott B Patten, 2002 Ashley Publishing.

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