Weight Loss Supplements Study
Effects of a Stimulant-Free Weight Loss
Supplement on Body Weight and Fat Loss in Obese
Weight Loss Supplement Study Background
Stimulants, such as ephedrine and caffeine and their herbal counterparts,
have proved effective in facilitating body weight loss, but their use
is controversial due to their undesired effects. Other nutraceuticals
have shown moderate success in reducing body weight, whereas several other
compounds have demonstrated little or no effect. Therefore, a tolerable
and effective nutraceutical that can increase energy expenditure and/or
decrease caloric intake is desirable for body weight reduction.
Weight Loss Supplement Study Aim
Assess the tolerability and effectiveness of a novel, stimulant-free,
dietary supplement containing glucomannan, chitosan, fenugreek, Gymnema
sylvestre, and vitamin C on body weight and fat loss and change in body
composition in obese adults.
Weight Loss Supplement Study Methods
In this single-center, prospective, randomized, double-blind, placebo-controlled
study conducted at the University of Guelph (Guelph, Ontario, Canada),
obese adults (aged 20-50 years; body mass index [BMI], 30 kg/m2) were
randomized to the treatment or placebo group. The treatment group received
6 capsules of a dietary supplement containing a proprietary blend of glucomannan,
chitosan, fenugreek, G sylvestre, and vitamin C daily for 6 weeks, and
the placebo group received 6 capsules of rice flour daily for 6 weeks.
Weight Loss Supplement Study Results
24 subjects were assigned to the treatment group (8 women, 4 men) or the
placebo group (9 women,3 men). No significant changes in the consumption
of total calories; the percentage of calories ingested as carbohydrates,
fat, or protein; or activity levels were found in either group throughout
the study. Compared with the placebo group, the treatment group lost significantly
more body weight, percentage of body fat, and absolute fat mass. The treatment
group also experienced a significantly greater reduction in upper abdominal
circumference, waist circumference, and hip circumference compared with
the placebo group. No significant changes in heart rate or blood pressure
were found in either group. Both the treatment and the placebo were well
tolerated.
Weight Loss Supplement Study Conclusion
The combination of glucomannan, chitosan, fenugreek, G sylvestre, and
vitamin C results in significant body weight and fat loss in obese adults
within the context of this study.
Source: 2003 Excerpta Medica Inc. All rights
reserved.
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