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Weight Loss Supplements Study
Effects of Stimulant-Free Supplement or Body Weight and Fat Loss
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Weight Loss Supplements Study

Effects of a Stimulant-Free Weight Loss Supplement on Body Weight and Fat Loss in Obese

Weight Loss Supplement Study Background
Stimulants, such as ephedrine and caffeine and their herbal counterparts, have proved effective in facilitating body weight loss, but their use is controversial due to their undesired effects. Other nutraceuticals have shown moderate success in reducing body weight, whereas several other compounds have demonstrated little or no effect. Therefore, a tolerable and effective nutraceutical that can increase energy expenditure and/or decrease caloric intake is desirable for body weight reduction.

Weight Loss Supplement Study Aim
Assess the tolerability and effectiveness of a novel, stimulant-free, dietary supplement containing glucomannan, chitosan, fenugreek, Gymnema sylvestre, and vitamin C on body weight and fat loss and change in body composition in obese adults.

Weight Loss Supplement Study Methods
In this single-center, prospective, randomized, double-blind, placebo-controlled study conducted at the University of Guelph (Guelph, Ontario, Canada), obese adults (aged 20-50 years; body mass index [BMI], 30 kg/m2) were randomized to the treatment or placebo group. The treatment group received 6 capsules of a dietary supplement containing a proprietary blend of glucomannan, chitosan, fenugreek, G sylvestre, and vitamin C daily for 6 weeks, and the placebo group received 6 capsules of rice flour daily for 6 weeks.

Weight Loss Supplement Study Results
24 subjects were assigned to the treatment group (8 women, 4 men) or the placebo group (9 women,3 men). No significant changes in the consumption of total calories; the percentage of calories ingested as carbohydrates, fat, or protein; or activity levels were found in either group throughout the study. Compared with the placebo group, the treatment group lost significantly more body weight, percentage of body fat, and absolute fat mass. The treatment group also experienced a significantly greater reduction in upper abdominal circumference, waist circumference, and hip circumference compared with the placebo group. No significant changes in heart rate or blood pressure were found in either group. Both the treatment and the placebo were well tolerated.

Weight Loss Supplement Study Conclusion
The combination of glucomannan, chitosan, fenugreek, G sylvestre, and vitamin C results in significant body weight and fat loss in obese adults within the context of this study.

Source: Excerpta Medica Inc. All rights reserved.

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