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Dexfenfluramine Patients Study

A study published in the Journal of the American College of Cardiology, looked at the condition of people who took the controversial weight loss drug dexfenfluramine.

The dexfenfluramine study looked at 941 patients. Two-thirds had taken the drug for up to three months and the rest took a placebo. The study found there was no evidence that the patients who developed valve problems got worse.

The leader of the dexfenfluramine study, Dr. Neil Weissman of the Washington Hospital Center in Washington, D.C., said longer-term studies are needed before anyone can conclude definitively that heart damage from the diet drugs goes away.

A study on dexfenfluramine published last week in Circulation, a journal of the American Heart Association, also suggested that the leaky valve problems typically are not severe and may regress after the drug is discontinued.

That study, led by Dr. Bruce Shively of the Oregon Health Sciences University in Portland, compared 223 patients who had taken the drug for an average of seven months against a control group of 189.