Possible Side Effects of Weight Loss Drugs
Most side effects of these medications
are mild and usually improve with continued treatment. Rarely, serious
and even fatal outcomes have been reported. Two approved appetite-suppressant
medications that affect serotonin release and reuptake have been withdrawn
from the market (fenfluramine, dexfenfluramine). Medications that affect
catecholamine levels (such as phentermine, diethylpropion, and mazindol)
may cause symptoms of sleeplessness, nervousness, and euphoria (feeling
of well-being).
Sibutramine acts on both the serotonin
and catecholamine systems, but unlike fenfluramine and dexfenfluramine,
sibutramine does not cause release of serotonin from cells. The primary
known side effects of concern with sibutramine are elevations in blood
pressure and pulse, which are usually small but may be significant in
some patients. People with poorly controlled high blood pressure, heart
disease, irregular heart beat, or history of stroke should not take sibutramine,
and all patients taking the medication should have their blood pressure
monitored on a regular basis.
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Note About Weight Loss Pills
To reduce health risks, do not buy weight loss pills or supplements
without first consulting your doctor. And when taking weight loss
drugs or pills, be sure to check in with your doctor regularly.
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