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Aspartame & Weight ControlThis study investigated whether the addition of the high-intensity sweetener aspartame to a multidisciplinary weight-control program would improve weight loss and long-term control of body weight. One hundred sixty-three obese women were randomly assigned to consume or to abstain from aspartame-sweetened foods and beverages during 16 wk of a 19-wk weight-reduction program (active weight loss), a 1-year maintenance program, and a 2-year follow-up period. Women in both treatment groups lost approximately 10 percent of initial body weight (10 kg) during active weight loss. Among women assigned to the aspartame-treatment group, aspartame intake was positively correlated with percentage weight loss during active weight loss. During maintenance and follow-up, participants in the aspartame group experienced a 2.6 percent (2.6 kg) and 4.6 percent (4.6 kg) regain of initial body weight after 71 and 175 wk, respectively, whereas those in the no-aspartame group gained an average of 5.4 percent (5.4 kg) and 9.4 percent (9.4 kg), respectively. The aspartame group lost significantly more weight overall and regained significantly less weight during maintenance and follow-up than did the no-aspartame group. Percentage weight losses at 71 and 175 wk were also positively correlated with exercise and self-reported eating control. These data suggest that participation in a multidisciplinary weight-control program that includes aspartame may facilitate the long-term maintenance of reduced body weight. Source: Blackburn GL, Kanders BS, Lavin PT, Keller SD, Whatley J. Center for the Study of Nutrition Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. 1997 Return to Weight Loss Research Articles |
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