Reduced Stomach Capacity in Obese Subjects
After Dieting
The objective of the study was to assess
the change in gastric capacity of obese subjects consuming a hypo-energetic
diet. Otherwise healthy, obese subjects participated in a prospective
controlled study as hospital outpatients. Fourteen (11 females, 3 males)
subjects were assigned to the diet group and 9 (7 females, 2 males) were
assigned to the control group. Subjects in the diet group were provided
a 2508-kJ/d(600 kcal/d) formula diet for 4 wk. Subjects in the control
group ate ad libitum for 4 wk. Gastric capacity was determined before
the study and 4 wk later by oral insertion of a latex gastric balloon
after an overnight fast. The balloon was infused with water at a rate
of 100 mL/min, with pauses for measuring intragastric pressure, until
no further distension was tolerated. Two indexes for estimating gastric
capacity were used based on subjective and objective criteria: 1) the
maximal volume that could be tolerated, and 2) the volume required to
produce a rise in water pressure of 5 cm. Subjects in the diet group,
who lost a mean of 9.1 kg, showed a 27 percent reduction in gastric capacity
based on the first index and a 36 percent reduction based on the second
index. For the control subjects, gastric capacity did not change significantly
with use of either index. The results demonstrate a reduction in gastric
capacity in obese subjects after a restricted diet.
Source: Geliebter A, Schachter S, Lohmann-Walter
C, Feldman H, Hashim SA. Department of Medicine and Psychiatry, St. Lukes-Roosevelt
Hospital, Columbia University College of Physicians and Surgeons, New
York, NY 10025, USA. 1996
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