Very Low Calorie Diets VLCD vs. Low Calorie
Diets (LCD) in the Long-Term Treatment of Obesity
Weight Study Aim
To compare the long-term effects of three different programs including
initial 6 weeks (V)LCD diets 420 kcal/d, 530 kcal/d, 880 kcal/d) on sustained
weight loss, attrition and obesity associated conventional cardiovascular
risk factors.
Weight Study Design
Prospective, randomized clinical 52 weeks trial. Two weeks of a booster
(V)LCD period after week 26. Setting was a University outpatient obesity
clinic. Subjects included 93 middle-aged obese patients (30 men), initial
mean BMI 38.7 kg/m2, age 20-65 y, from the waiting list.
Weight Study Results
One year attrition (30-45 percent), sustained weight loss (8-15 percent
of initial body weight) and changes in obesity associated risk parameters
were similar in all three groups. Fewer adverse events were reported in
the LCD group.
Weight Study Conclusion
The results compare favorably with most previous reports of similar design.
VLCD (420 kcal or 530 kcal/ d and LCD 880 kcal/d) were equally effective
in long term treatment of obesity. The tendency to less side effects with
LCD suggests that such preparations deserve further attention.
Source: Rossner S, Flaten H. Obesity Unit,
Karolinska Hospital, Stockholm, Sweden. 1997
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