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Weight Loss Diet and GhrelinWhy Diet and Exercise Fail Unlike after gastric bypass surgery induced weight loss, after diet-induced weight loss, researchers have observed a rise in blood-ghrelin levels. In addition to increasing food intake, they discovered that ghrelin also slows down the body's metabolic rate. Ghrelin, it seems, is on a mission to maintain body weight.
This preservation phenomenon could be why "weight loss occurs fast at first but then slows as the body fights vigorously to regain this predetermined set point," says Dr. Michael Meguid, Nutrition editor-in-chief and director of surgical research at the State University of New York's Upstate Medical University in Syracuse, N.Y. Ghrelin triggers hunger, says Frank Chae, assistant professor surgery and head of obesity surgery at the University of Colorado Health and Sciences Center in Denver. "Hunger is the chief reason for which most dieters quit dieting and regain the excess weight," he says. For final page, click Ghrelin
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